Prolonged Multimodal Analgesia for Post-Discharge Pain Control After Primary Total Hip Arthroplasty
Completed · Not applicable
Conditions studied: Osteoarthritis, Hip
In brief
This is a prospective, three-arm, comparative study with a provider-crossover design. The first arm will comprise the standard of care pain regimen after discharge, which comprises PRN oxycodone, tramadol, and acetaminophen. The second arm will comprise a multimodal pain regimen; however, patients will still be routinely provided PRN oxycodone and tramadol to use on an as needed basis. The third arm will comprise a multimodal pain management protocol, which does not routinely allow for opioid consumption. However, patients will be provided a one week supply of oxycodone and tramadol for emergency pain relief only.
Key facts
- Study ID
- NCT03358888
- Run by
- Rothman Institute Orthopaedics
- People needed
- 228
- Starts
- 2017-06-05
- Expected to finish
- 2018-02-28
- Last updated by the study team
- 2019-01-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients undergoing unilateral, primary cementless THA with underlying diagnosis of osteoarthritis.
- ASA I - III
- Spinal anesthesia
- Male and Female over 18 who are willing and able to provide informed consent
You may not qualify if…
- Opioid use within 3 months prior to surgery
- General anesthesia
- Non-english speaking
- ASA IV or greater
- Allergy/contraindications to protocol medications
- Renal insufficiency with Cr > 2.0 or hepatic failure
- Sensory/motor disorder involving the operative limb
- Planned or unplanned discharge to rehab
- Length of stay >3 days
- Revision or conversion THA
- Cigarette smokers
Where it is running
- Rothman Institute — Philadelphia, Pennsylvania, United States
Full record on ClinicalTrials.gov
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