Engineering Gut Microbiome to Target Breast Cancer

Completed · Not applicable

Conditions studied: Breast Cancer

In brief

The purpose of this study is to find out if using probiotics will help the body's immune system react to breast cancer. New studies showed that diverse species of bacteria inside the bowel might help improve immune system, particularly the ability of immune system to recognize cancer. This study will investigate how probiotics will affect the subjects' immune system on breast cancer.

Key facts

Study ID

NCT03358511

Run by

Mayo Clinic

People needed

7

Starts

2017-10-11

Expected to finish

2020-05-19

Last updated by the study team

2020-05-21

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Post-menopausal females ≥ 18 years of age
• Histologically confirmed adenocarcinoma of the breast ≥1.0 cm operable stage I-III
• Must have adequate organ function,
• Not receive systemic neoadjuvant therapy
• Be willing to provide tissue, blood, and stool samples for research study.
• Must not have taken any probiotics in the past 60 days prior to enrollment.

You may not qualify if…

• Patients with autoimmune disease, immune deficiency such as HIV, irritable bowel, known diverticulosis, and other serious GI conditions at treating physician's discretion will be excluded.

Where it is running

• Mayo Clinic in Florida — Jacksonville, Florida, United States

Full record on ClinicalTrials.gov

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