A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of MEDI5884 in Adults With Stable Coronary Heart Disease

Completed · Phase 2 · Has a placebo group

Conditions studied: Stable Coronary Heart Disease

In brief

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamic Effects of MEDI5884 in Adults With Stable Coronary Heart Disease.

Key facts

Study ID

NCT03351738

Run by

MedImmune LLC

People needed

133

Starts

2017-12-13

Expected to finish

2018-11-09

Last updated by the study team

2020-03-23

Who can join

Age: 45 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of stable coronary heart disease prior to screening
• Currently receiving high intensity statin(s)

You may not qualify if…

• Unstable cardiovascular conditions
• Any planned arterial revascularizations
• Fasting Laboratory values at screening: Triglycerides > 500 mg/dl, Low Density Lipoprotein-Cholesterol > 100 mg/dL
• Any disease or condition or laboratory value that would place the participant at an unacceptable risk.

Where it is running

• Research Site — Anniston, Alabama, United States
• Research Site — Huntsville, Alabama, United States
• Research Site — El Cajon, California, United States
• Research Site — Lincoln, California, United States
• Research Site — Northridge, California, United States
• Research Site — Waterbury, Connecticut, United States
• Research Site — Fleming Island, Florida, United States
• Research Site — Jacksonville, Florida, United States
• Research Site — Pembroke Pines, Florida, United States
• Research Site — Port Orange, Florida, United States
• Research Site — Savannah, Georgia, United States
• Research Site — Evanston, Illinois, United States
• Research Site — Indianapolis, Indiana, United States
• Research Site — Louisville, Kentucky, United States
• Research Site — Fargo, North Dakota, United States
• Research Site — Cincinnati, Ohio, United States
• Research Site — Marion, Ohio, United States
• Research Site — Stow, Ohio, United States
• Research Site — Oklahoma City, Oklahoma, United States
• Research Site — Rapid City, South Dakota, United States
• Research Site — Kingsport, Tennessee, United States
• Research Site — McAllen, Texas, United States
• Research Site — San Antonio, Texas, United States

Full record on ClinicalTrials.gov

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