Combining Acceptance and Commitment Therapy With Exposure and Response Prevention to Enhance Treatment Engagement

Completed · Not applicable

Conditions studied: Obsessive-Compulsive Disorder

In brief

The aim of the study was to evaluate whether integrating Acceptance and Commitment Therapy (ACT) with Exposure and Response Prevention (ERP) increases the acceptability, tolerability, and adherence with ERP techniques relative to ERP without ACT. Fifty-eight adults with a DSM-IV diagnosis of Obsessive-Compulsive Disorder (OCD) received 16 twice-weekly sessions (2 hours per session) of either ERP with the inclusion of ACT techniques (ERP+ACT; n = 30) or ERP alone (n = 28). Assessments using interviews, self-report questionnaires, and behavioral observations were conducted at pre- and post-test, and at 6 month follow-up. Specific hypotheses were: 1) Patients receiving ERP+ACT will report greater treatment acceptability, and show higher quantity and quality of completed self-directed ERP assignments, relative to patients receiving standard ERP; 2) Both ERP and ERP+ACT will lead to clinically significant reductions in OCD symptoms from pre- to post-test and from pre-test to follow-up.

Key facts

Study ID

NCT03343106

Run by

Utah State University

People needed

58

Starts

2011-07-12

Expected to finish

2017-01-09

Last updated by the study team

2017-11-17

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Current DSM-IV-TR principal diagnosis of OCD for at least 1 year
• Willing to attend all 16 therapy sessions
• Fluent in English
• No previous Cognitive Behavior Therapy or Acceptance and Commitment Therapy for OCD
• If on medication for OCD, willing to remain at a fixed dose while participating in the study

You may not qualify if…

• Current severe depression or suicidal ideation
• Current substance abuse or dependence
• Current mania, psychosis, or borderline or schizotypal personality disorder

Where it is running

• University of North Carolina at Chapel Hill — Chapel Hill, North Carolina, United States
• Utah State University — Logan, Utah, United States

Full record on ClinicalTrials.gov

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