High Intensity Focused Ultrasound Treatment of Breast Tumors. BRIFU Study

Recruiting now · Not applicable

Conditions studied: Breast Cancer Female

In brief

Monocentric prospective study evaluating the efficacy of High intensity focused ultrasound (HIFU) in breast tumors.

Key facts

Study ID

NCT03342625

Run by

Institut Bergonié

People needed

15

Starts

2018-06-07

Expected to finish

2027-01-01

Last updated by the study team

2025-10-02

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Histologically proven infiltrating ductal carcinoma with the analysis of hormone receptors, tumor grade, Her-2 expression.
• T0 lesion, unifocal or plurifocal, with or without micro-calcifications associated, measuring 15 mm maximum major axis on ultrasound.
• Clinical N0.
• Bra cup size greater than or equal to B.
• Markable and identifiable lesion in MRI.
• Indication of partial or total mastectomy in case of multifocal lesions or extensive calcification associated with axillary surgery.
• Breast assessment performed by a referent radiologist: Mammography, ultrasound, clinical examination.
• No contraindication to MRI.

You may not qualify if…

• Infiltrating lobular carcinoma and Pure ductal carcinoma in situ.
• Bilateral lesion.
• Non-detectable MRI lesions, within 10 mm of the skin, greater than 15 mm on ultrasound.
• Unifocal palpable tumor.
• Cup size bra equal to A.
• Cutaneous lesion on the breast to be treated by HIFU.
• Impossibility of ventral decubitus immobility, extended arm, during 1 hour.
• Pregnant or postpartum patient.
• Patient participating in another interventional clinical trial within 30 days of enrollment and during the trial.

Where it is running

• Institut Bergonie — Bordeaux, France (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.