Balance and Anti-Epileptic Drugs

Completed · Not applicable

Conditions studied: Epilepsy

In brief

Patients with epilepsy exercise less than the general population. A barrier to exercise may be the effect of antiepileptic drugs on balance and reaction time. This proposal endeavors to study the effect of two common antiepileptic drugs (levetiracetam and lamotrigine) on balance and reaction time using a Wii balance board and reaction time test. This will be tested at descending doses in an epilepsy monitoring unit. Drug levels will be monitored, as well as center of pressure, and reaction time.

Key facts

Study ID

NCT03338478

Run by

Erik J. Kobylarz

People needed

42

Starts

2017-12-01

Expected to finish

2018-05-30

Last updated by the study team

2018-08-06

Who can join

Age: 16 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Focal or generalized epilepsy
• On a stable dose of AEDs defined by no medication changes within the last month.
• On levetiracetam or lamotrigine monotherapy

You may not qualify if…

• Inability to stand independently for 30 seconds
• Peripheral neuropathy
• History of stroke or previous brain surgery
• Seizure within last 24 hours

Where it is running

• Dartmouth-Hitchcock Medical Center — Lebanon, New Hampshire, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.