Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder
Completed
Conditions studied: Bipolar Disorder, Bipolar I Depression, Bipolar II Depression, Bipolar Depression, Depression, Major Depressive Episode
In brief
Lithium is highly effective in the treatment of bipolar disorder. This study aims to investigate, for the first time, the impact of lithium monotherapy on the structural and functional connectivity of the brain using MRI imaging.
Key facts
- Study ID
- NCT03336918
- Run by
- Brigham and Women's Hospital
- People needed
- 81
- Starts
- 2017-12-07
- Expected to finish
- 2025-06-30
- Last updated by the study team
- 2026-07-16
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.
Where it is running
- Cleveland Clinic Foundation Center for Behavioral Health — Cleveland, Ohio, United States
Full record on ClinicalTrials.gov
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