A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLL
Running, not enrolling · Phase 3
Conditions studied: Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma
In brief
To compare efficacy between zanubrutinib versus bendamustine and rituximab in patients with previously untreated CLL/SLL, as measured by progression free survival assess by Independent Central Review.
Key facts
- Study ID
- NCT03336333
- Run by
- BeiGene
- People needed
- 590
- Starts
- 2017-10-31
- Expected to finish
- 2027-10-31
- Last updated by the study team
- 2026-03-09
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Northwestern University — Chicago, Illinois, United States
- Dana Farber Cancer Institute — Boston, Massachusetts, United States
- Research Medical Center — Kansas City, Missouri, United States
- Washington University — St Louis, Missouri, United States
- Comprehensive Cancer Centers of Nevada — Las Vegas, Nevada, United States
- Summit Medical Group — Florham Park, New Jersey, United States
- Icahn School of Medicine At Mount Sinai — New York, New York, United States
- Columbia University Medical Center — New York, New York, United States
- University of Rochester — Rochester, New York, United States
- Duke University — Durham, North Carolina, United States
- Oregon Health and Science University — Portland, Oregon, United States
- Prairie Lakes Healthcare System — Watertown, South Dakota, United States
- Tennessee Oncology, Pllc Nashville — Nashville, Tennessee, United States
- Joe Arrington Cancer Research and Treatment Center — Lubbock, Texas, United States
- University of Virginia — Charlottesville, Virginia, United States
- Va Puget Sound Health Care System — Seattle, Washington, United States
- Fred Hutchinson Cancer Research Center — Seattle, Washington, United States
- Concord Repatriation General Hospital — Concord, New South Wales, Australia
- The Tweed Valley Hospital — Cudgen, New South Wales, Australia
- Calvary Mater Newcastle — Waratah, New South Wales, Australia
- Westmead Hospital — Westmead, New South Wales, Australia
- Icon Cancer Centre Wesley — Auchenflower, Queensland, Australia
- Princess Alexandra Hospital — Brisbane, Queensland, Australia
- Royal Brisbane and Womens Hospital — Herston, Queensland, Australia
- Augusta University — Augusta, Georgia, United States
Full record on ClinicalTrials.gov
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