Improving the Diagnosis of Common Variable Immune Deficiency

Completed

Conditions studied: CVI - Common Variable Immunodeficiency

In brief

This is an observational, case-control study with a single blood draw among two cohorts, patients with antibody deficiency (e.g., CVID) and healthy controls. Samples will be analyzed by mass cytometry (CyTOF) to examine the major signaling pathways of all circulating innate and adaptive immune cell types, as well as whole exome sequencing. The goal is to improve our general understanding of the human immune response to infections and the diagnosis of CVID.

Key facts

Study ID

NCT03335605

Run by

University of California, Los Angeles

People needed

24

Starts

2019-05-01

Expected to finish

2022-06-01

Last updated by the study team

2026-04-20

Who can join

Age: any. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Diagnosis of antibody deficiency (CVID)

Where it is running

• UCLA — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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