Inflammasomes in Cell Death in FTMH, ERM, and RRD

Completed

Conditions studied: Retinal Detachment, Full Thickness Macular Hole, Epiretinal Membrane

In brief

Prospective study evaluating the role of inflammasomes in cell death in retinal detachment, full thickness macular hole, and epiretinal membrane. The investigators are collecting vitreous and subretinal fluid samples from patients with these conditions and evaluating activity of the inflammasome pathway with established assays.

Key facts

Study ID

NCT03332758

Run by

Allen C. Ho, MD

People needed

41

Starts

2017-09-08

Expected to finish

2018-05-01

Last updated by the study team

2018-08-17

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient of the Wills Eye Hospital Retina service and Mid-Atlantic Retina offices.
• Volunteer patients age 18 years and older.
• Healthy enough to participate in the study.
• Willing and able to consent to participation in the study.
• Diagnosis of rhegmatogenous retinal detachment treated with external drainage of subretainl fluid, rhegmatogenous retinal detachment treated with pars plana vitrectomy, or full thickness macular hole treated with pars plana vitrectomy

You may not qualify if…

• Presence of tractional retinal detachment
• History of trauma
• Presence of proliferative vitreoretinopathy
• History of prior retinal detachment repair or any prior retina surgery or laser treatment e. Any preexisting retinal disease (including diabetic retinopathy, age related macular degeneration, retinal vein or artery occlusion, other retinal vascular disease, inherited retinal degeneration, uveitis)

Where it is running

• MidAtlantic Retina-Wills Eye Hospital — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.