Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?

Completed · Phase 4 · Has a placebo group

Conditions studied: Knee Osteoarthritis, Knee Rheumatism

In brief

One common anesthetic that is performed for total knee replacement surgery is spinal anesthesia with an adductor canal regional block, which involves injecting numbing medication in the thigh region for pain control after surgery. The aim of this study is to determine whether the addition of another regional block called obturator nerve block, which involves injecting numbing medication in the upper thigh region, will improve pain control after surgery while not sacrificing mobility after surgery.

Key facts

Study ID

NCT03326999

Run by

Icahn School of Medicine at Mount Sinai

People needed

60

Starts

2017-12-11

Expected to finish

2018-12-18

Last updated by the study team

2020-09-30

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients scheduled to undergo total knee arthroplasty
• Planned use of regional anesthesia for procedure
• Willing and able to provide informed consent

You may not qualify if…

• Patients on immunosuppressive therapy
• Patients with history of diabetes
• Patients with lower limb neuropathy
• Patients with history of chronic opioid use for > 3 months, including but not limited to, fentanyl, morphine, oxycodone, methadone
• Patients with known allergy or intolerance to any drug used in the study
• Patients with history of alcohol or drug abuse
• Patients with history of intolerance of nonsteroidal anti-inflammatory drugs
• Patients with hepatic or renal insufficiency
• ASA score of 4 or greater

Where it is running

• Icahn School of Medicine at Mount Sinai — New York, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.