Rod Sensitivity in Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP)

Completed

Conditions studied: Retinitis Pigmentosa, AMD

In brief

A new fundus-guided microperimeter (MP-3S) has been developed by Nidek, Inc. to track the fundus of the patient and present stimuli in specific anatomically-defined locations. Furthermore, this tracking means that exactly the same locations can be tested on subsequent (follow-up) visits. The investigators will use a method called two-color perimetry to map rod and cone sensitivity on this device. With this technique, the sensitivity difference (blue-red) to chromatic test stimuli can be used to determine whether rods, cones or both photoreceptor systems mediate the threshold at a given location in the macula.

Key facts

Study ID

NCT03322930

Run by

Retina Foundation of the Southwest

People needed

40

Starts

2017-10-01

Expected to finish

2019-03-01

Last updated by the study team

2019-12-23

Who can join

Age: 10 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• clear media
• diagnosis of RP or non neovascular AMD
• normal volunteers

You may not qualify if…

• exudative AMD
• other eye diseases that could cause vision loss
• physical ailments that would preclude comfortable testing
• unable to provide informed consent

Where it is running

• Retina Foundation of the Southwest — Dallas, Texas, United States

Full record on ClinicalTrials.gov

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