Neostigmine For Snoring During DISE

Stopped early · Early Phase 1

Conditions studied: Snoring

In brief

The study team is seeking a novel treatment for snoring involving local application of a nerve stimulant medication, neostigmine. In this study, neostigmine will be injected into 5 sites of the soft palate during a standard procedure, drug-induced sleep endoscopy, to evaluate the effect on snoring.

Key facts

Study ID

NCT03316963

Run by

Emory University

People needed

1

Starts

2017-11-14

Expected to finish

2019-03-19

Last updated by the study team

2019-07-02

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Snoring or mild obstructive sleep apnea
• English-speaking
• Greater than 18 years old
• Able to give informed consent

You may not qualify if…

• On active anti-coagulation medication
• Pregnant women
• Hypersensitivity to neostigmine
• Peritonitis or mechanical obstruction of the intestinal or urinary tract
• Coronary artery disease
• Cardiac arrhythmia
• Recent acute coronary syndrome
• Myasthenia gravis

Where it is running

• Raj C. Dedhia — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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