Achilles Pain Block
Completed · Phase 2/Phase 3
Conditions studied: Achilles Tendon Pain
In brief
The purpose of this study is to better understand how the peripheral and central nervous system interact to produce the sensation of pain and motor patterns in patients with achilles tendinopathy (AT). These findings will motivate the development of future clinical studies that incorporate knowledge about pain processing and movement strategies in patients with tendinopathy. Participants with achilles tendinopathy will receive an anesthetic injection to the achilles tendon in order to examine how reduced pain, detected by the peripheral nervous system, alters task performance and perception of pain. We hypothesize that there are factors within the central nervous system that contribute to continued pain and disability in patients with chronic AT.
Key facts
- Study ID
- NCT03316378
- Run by
- Ruth Chimenti
- People needed
- 46
- Starts
- 2016-01-28
- Expected to finish
- 2018-05-10
- Last updated by the study team
- 2019-07-05
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Clinical diagnosis of chronic (>3 months) AT, consisting of pain with pressure at the achilles tendon and report of pain that is aggravated by physical activity
You may not qualify if…
- History of foot or ankle surgery, bilateral lateral epicondyle tendinopathy
- Comorbidity that would be aggravated by placing hand in water (Raynaud's, thoracic outlet syndrome)
- Comorbidity (e.g. stroke, neurological disorder) that limits ability to participate in exercise
- Comorbidity (e.g. rheumatic disease, fibromyalgia) that contributes to pain with activity
- Peripheral neuropathy
- Previous adverse response to a local anesthetic injection
- Are pregnant
- Are a ballroom dancer
- For control participants
- Inclusion Criteria:
- Sex, Age and BMI-matched to participant with AT
- Exclusion Criteria:
- No history of tendinopathy
- No condition that limited activity in the past 6 months
- History of foot or ankle surgery, bilateral lateral epicondyle tendinopathy
- Comorbidity that would be aggravated by placing hand in water (Raynaud's, thoracic outlet syndrome)
- Comorbidity (e.g. stroke, neurological disorder) that limits ability to participate in exercise
- Comorbidity (e.g. rheumatic disease, fibromyalgia) that contributes to pain with activity
- Peripheral neuropathy
- Are pregnant
- Are a ballroom dancer
Where it is running
- University of Iowa — Iowa City, Iowa, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.