Berlin-Brandenburg Pregnancy Cohort

Recruiting now

Conditions studied: Preeclampsia, Pregnancy Complications, Diabetes Mellitus in Pregnancy

In brief

This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.

Key facts

Study ID

NCT03313024

Run by

Charite University, Berlin, Germany

People needed

1580

Starts

2017-09-26

Expected to finish

2027-10-01

Last updated by the study team

2018-08-14

Who can join

Age: 18 and older, up to 45. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• healthy pregnant women after giving informed consent
• pregnant with diagnosis of preeclampsia, gestational hypertension or gestational diabetes

You may not qualify if…

• infections
• alcohol and drug abuse
• manifest and chronic diseases

Where it is running

• Experimental and Clinical Research Center (ECRC) — Berlin, Germany (enrolling)

Full record on ClinicalTrials.gov

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