Positron Emission Tomography (PET) Study in Patients With Alzheimer's Disease

Stopped early · Phase 1

Conditions studied: Alzheimer's Disease

In brief

To investigate the brain receptor occupancy of idalopirdine in patients with Alzheimer's disease (AD)

Key facts

Study ID

NCT03307993

Run by

H. Lundbeck A/S

People needed

3

Starts

2017-09-22

Expected to finish

2018-02-19

Last updated by the study team

2018-04-04

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• The patient has probable AD diagnosed according to National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's disease and Related Disorders Association (NINCDS-ADRDA) criteria.
• The patient has had a positive amyloid PET scan, which in the opinion of the principal investigator is consistent with a diagnosis of AD.
• The patient has a Mini Mental State Examination (MMSE) score at screening of at least 15 and no greater than 22.
• The patient has a knowledgeable and reliable caregiver who will accompany the patient to all clinic visits during the study and answer questions about the patient.
• The patient is a man or woman of at least 50 years of age and has a body mass index (BMI) ≥ 18.5 kg/m2.

You may not qualify if…

• The patient has evidence of any clinically significant neurodegenerative disease, or other serious neurological disorders other than AD including but not limited to Lewy body dementia, fronto-temporal dementia, Parkinson's disease, Huntington's disease, major cortical stroke, major head trauma, primary or secondary cerebral neoplasia or systemic medical diseases that are, in the investigator's opinion, likely to affect central nervous system functioning and may influence the outcome or analysis of the scan results.
• The patient is, in the investigator's opinion, unlikely to comply with the protocol or is unsuitable for any reason.

Where it is running

• Johns Hopkins Hospital — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.