Youth Opioid Recovery Support: A Developmentally-specific Intervention for Home Delivery of Extended Release Naltrexone

Completed · Not applicable

Conditions studied: Opioid-Related Disorders

In brief

Opioid addiction among youth (including both adolescents and young adults) is a growing health problem with catastrophic consequences for young people and their families. The current opioid epidemic disproportionately affects youth. Furthermore, compared to adults, adolescents and young adults tend to have poorer engagement in and response to treatment than older adults. Relapse prevention medications are the clear standard of care for the treatment of opioid addiction in adults, but the evidence base for effectiveness including implementation is not well-established in youth, and concerns from the field emphasize poor adherence and retention. Further there is no consensus regarding models of care, psychosocial treatments and platforms for delivery of medications. Extended release naltrexone (XR-NTX) has proven effectiveness in adults and is a promising pharmacotherapy for youth, but the field needs further clarification of its optimal use and delivery in this target population, in the context of developmentally informed models of care. There is inadequate current capacity for specialty opioid specific treatment that integrates pharmacotherapy (relapse prevention medication) with psychosocial treatment in a context that is youth welcoming and family empowering.

Key facts

Study ID

NCT03306368

Run by

Potomac Health Foundations

People needed

40

Starts

2018-02-01

Expected to finish

2019-12-01

Last updated by the study team

2021-09-23

Who can join

Age: 18 and older, up to 26. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Young adults age 18-26 with OUD who present for an index episode of residential/inpatient opioid detoxification and seek treatment with XR-NTX at Mountain Manor Treatment Center (MMTC).

You may not qualify if…

• Liver function tests (LFTs) > 5x upper limit of normal
• Psychiatric or medical instability (eg suicidailty, psychosis, Sickle Cell disease with frequent crises, etc) that would preclude participation in the trial
• Living situation (location greater than 60 miles from the center, homelessness) that would preclude participation in the trial

Where it is running

• Mountain Manor Treatment Center — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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