The GEOLynch Cohort Study

Recruiting now

Conditions studied: Lynch Syndrome, Neoplasms, Hereditary Nonpolyposis Colorectal Cancer, Colorectal Neoplasms

In brief

The GEOLynch cohort study has been established to investigate the influence of genetic, environmental and other factors on tumour risk in persons with Lynch syndrome.

Key facts

Study ID

NCT03303833

Run by

Wageningen University

People needed

1000

Starts

2006-07-01

Expected to finish

2030-12-01

Last updated by the study team

2017-10-06

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Persons with a known mutation in a gene that causes Lynch syndrome, i.e. with an inherited monoallelic pathogenic germline mutation in either the MLH1, MSH2, MSH6, PMS2 or EPCAM gene.
• Aged between 18 and 80 years at inclusion.

You may not qualify if…

• Additional carrier of another hereditary colon cancer predisposition syndrome (e.g. FAP)
• (Chronic) Inflammatory bowel disease
• Non-Dutch speaking
• Dementia or another mental condition that makes it impossible to fill out questionnaires
• Terminally ill persons

Where it is running

• Wageningen University — Wageningen, Netherlands (enrolling)

Full record on ClinicalTrials.gov

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