Factors Influencing Pediatric Asthma

Completed · Not applicable

Conditions studied: Asthma in Children

In brief

Asthma is a chronic lung disease with serious morbidity and potential mortality. Multiple physiologic, environmental and social conditions impact the prevalence and severity of asthma. Even when diagnosed, effective control can be impeded by improper use of medication, not understanding or being unable to avoid environmental triggers, lack of continuity in follow-up care, and lack of an asthma action plan. American Indians are especially at-risk for health problems related to asthma. American Indians have the highest asthma rate among single-race groups; 18.5% of American Indians are diagnosed with asthma, while only 11% are diagnosed with asthma in the general population but little is known about why this is true. Asthma is a prototypic example of the interaction of biologic, environmental and psychosocial influences on disease and this study investigated the possible improvement in asthma control from an intensive educational intervention.

Key facts

Study ID

NCT03302962

Run by

Missouri Breaks Industries Research, Inc.

People needed

324

Starts

2013-03-14

Expected to finish

2017-05-25

Last updated by the study team

2017-10-05

Who can join

Age: 6 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Cases must be "American Indian" (eligibile for care within the Indian Health Service); and at least 2 of the following 3 criteria:
• a diagnosis of asthma on at least 2 occasions by more than one provider during the past 2 years.
• refills of asthma treatment medications on at least 2 occasions during the past 2 years.
• Improvement of spirometry FEV1 of 20% with use of albuterol MDI or nebulizer.
• Controls meet the same demographic criteria as cases, but must also meet all of the following criteria.
• No diagnosis of asthma by any provider during the past 2 years.
• No prescriptions of any asthma meds during the past 2 years.
• FEV1 on spirometry greater than 80% of predicted value Exclusion Criteria:

You may not qualify if…

• Birthweight less than 2500 grams
• Neonatal ventilator treatment
• Hospitalization at birth greater than 15 days.
• Congenital heart anomaly requiring surgery
• Diagnosis of cystic fibrosis
• Congenital lung, diaphragm, chest wall, or airway anomaly
• Diagnosis of pneumonia, pertussis, or tuberculosis within the past year
• Congenital muscular disorder

Where it is running

• Missouri Breaks Industries Research Inc. — Eagle Butte, South Dakota, United States

Full record on ClinicalTrials.gov

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