A Comparison of Non-invasive Ventilation Methods Used to Prevent Endotracheal Intubation Due to Apnea in Very Low Birth Weight Infants

Completed · Not applicable

Conditions studied: Apnea of Prematurity

In brief

The purpose of this study is to determine whether nasal intermittent positive pressure ventilation (NIPPV) reduces the need for endotracheal intubation in very low birth weight infants with persistent apnea who fail nasal continuous positive airway pressure (NCPAP).

Key facts

Study ID

NCT03298035

Run by

The University of Texas Health Science Center, Houston

People needed

19

Starts

2017-11-11

Expected to finish

2018-12-31

Last updated by the study team

2020-02-07

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Infants born at < 30 weeks gestational age who develop clinically significant apnea while on NCPAP > 6cm H2O or whose team is considering intubation due to apnea. Consider clinically significant apnea as 1 or more events treated with bag-mask ventilation or 3 episodes of apnea requiring stimulation within 1 hour.
• Infants on maximum caffeine therapy (10mg/kg/day)

You may not qualify if…

• Major congenital anomalies including congenital heart disease

Where it is running

• The University of Texas Health Science Center at Houston — Houston, Texas, United States

Full record on ClinicalTrials.gov

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