A Study of AG-120 (Ivosidenib) in Subjects With Mild or Moderate Hepatic Impairment or Normal Hepatic Function

Completed · Phase 1

Conditions studied: Hepatic Impairment

In brief

Study AG120-C-012 is a Phase 1, open-label, single-dose study designed to evaluate the PK, safety, and tolerability of a single 500 mg AG-120 (Ivosidenib) dose in subjects with mild or moderate hepatic impairment (HI) compared to subjects with normal hepatic function. The study will be conducted at 2 US centers.

Key facts

Study ID
NCT03282513
Run by
Agios Pharmaceuticals, Inc.
People needed
33
Starts
2017-09-26
Expected to finish
2018-03-31
Last updated by the study team
2018-04-27

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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