Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.

Completed

Conditions studied: Premature Infant, Patent Ductus Arteriosus, Hemodynamic Instability

In brief

The proposed research evaluates tissue oxygenation (StO2) as measured by resonance raman spectroscopy (RRS) in premature infants with and without patent ductus arteriosus (PDA). This is a prospective observational study of infants born at \< 30 weeks of gestation. The primary aim of this study is to determine if the difference in pre- and post-ductal StO2 as detected by RRS is more significant in premature infants with PDA in comparison to infants without PDA. The secondary aim of this study is to determine if the difference in pre- and post-ductal StO2 as detected by RRS is more significant in infant who develop serious adverse events.

Key facts

Study ID

NCT03277768

Run by

University of Florida

People needed

55

Starts

2015-05-01

Expected to finish

2018-08-23

Last updated by the study team

2019-09-10

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Infants < 30 weeks estimated gestational age

You may not qualify if…

• Infants with major congenital anomalies
• Infants >34 weeks post-menstrual age

Where it is running

• University of Florida — Gainesville, Florida, United States
• Boston Children's Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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