Effect of Androgen Deprivation Therapy on Cardiovascular Function in Prostate Cancer
Completed
Conditions studied: Prostate Cancer
In brief
The aim of this project is to determine whether androgen deprivation therapy (ADT) decreases left ventricular function in prostate cancer patients. If found successful, this may lead to improved cardiovascular health via treatment and/or lifestyle interventions in prostate cancer populations.
Key facts
- Study ID
- NCT03275181
- Run by
- Kansas State University
- People needed
- 18
- Starts
- 2017-08-01
- Expected to finish
- 2018-12-31
- Last updated by the study team
- 2025-09-02
Who can join
Age: 21 and older, up to 80. Sex: male. Healthy volunteers: accepted.
You may qualify if…
- Give voluntary consent to participate in the study
- (Group 1) Diagnosed prostate cancer patient/survivor with a history of androgen deprivation therapy treatment
- (Group 2) Diagnosed prostate cancer patient/survivor with no history of androgen deprivation therapy treatment
- (Group 3) Cancer free
You may not qualify if…
- History of clinical cardiovascular disease (Atherosclerotic cardiovascular disease (ASCVD) defined by history of acute coronary syndromes, myocardial infarction (MI), stable or unstable angina, coronary or other arterial revascularization, stroke, transient ischemia attack (TIA), or peripheral arterial disease presumed to be of atherosclerotic origin)
- Not met the above criteria
- Unable to provide informed consent
- History of smoking (within 6 months) or current smoker
- Major signs or symptoms suggestive of cardiovascular, pulmonary, or metabolic disease. These include pain, discomfort in the chest, neck, jaw, arms or other areas that may result form ischemia; shortness of breath at rest or with mild exertion; Dizziness or syncope; Orthopnea or paroxysmal nocturnal dyspnea; ankle edema; palpitations or tachycardia; intermittent claudication; known heart murmur; unusual fatigue or shortness of breath with usual activities
Where it is running
- Kansas State University - Clinical Integrative Physiology Laboratory — Manhattan, Kansas, United States
Full record on ClinicalTrials.gov
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