Study of Safety, Tolerability, Preliminary Efficacy of Intra-articular LNA043 Injections in Patients With Articular Cartilage Lesions and Knee Osteoarthritis.

Completed · Phase 2 · Has a placebo group

Conditions studied: Osteoarthritis

In brief

The purpose of this two-part study is to assess the efficacy, safety and tolerability of multiple intra-articular (i.a.) injections of LNA043, in regenerating the articular surface in patients with cartilage lesions of the knee (Part A) and knee osteoarthritis (Part B).

Key facts

Study ID
NCT03275064
Run by
Novartis Pharmaceuticals
People needed
142
Starts
2017-09-12
Expected to finish
2022-09-06
Last updated by the study team
2026-04-21

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

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