Mapping Disease Pathways for Biliary Atresia

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Conditions studied: Biliary Atresia

In brief

This project will primarily evaluate the developmental/genetic basis of biliary atresia, the most common cause of liver failure at birth, and which accounts of half of all liver transplants performed worldwide in children.

Key facts

Study ID

NCT03273049

Run by

University of Pittsburgh

People needed

1100

Starts

2016-07-21

Expected to finish

2035-07-21

Last updated by the study team

2026-08-10

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• living individuals who were diagnosed with Biliary Atresia and received or are about to receive a liver transplant from multiple participating centers (Children's Hospital of Pittsburgh, Kings College Hospital, Children's Hospital of Birmingham, and Hospital Sírio-Libanês).

You may not qualify if…

• No child participant in the care of the state will be enrolled, nor will patients in the care of temporary or informal guardians be enrolled

Where it is running

• UPMC Children's Hospital of Pittsburgh — Pittsburgh, Pennsylvania, United States (enrolling)

Full record on ClinicalTrials.gov

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