The Computed Tomography-derived Fractional Flow Reserve STAT Trial

Stopped early · Not applicable

Conditions studied: Heart Disease, Coronary, Chest Pain, Acute Coronary Syndrome

In brief

This study is designed to directly compare Standard Care and CT fractional flow reserve (CTFFR) for diagnosis of chest pain patients with definite coronary artery disease (CAD) on heart computed tomography (CT) scans.

Key facts

Study ID

NCT03263806

Run by

Corewell Health East

People needed

13

Starts

2017-08-24

Expected to finish

2018-04-04

Last updated by the study team

2018-07-03

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Emergency department chest pain suspicious for ACS based on history and physical examination.
• At least one biomarker (troponin) and electrocardiogram with no evidence of definite ACS.
• A completed CCTA demonstrating >50% but <90% stenosis of at least one coronary artery branch.
• CCTA test images with sufficient diagnostic quality for CTFFR analysis.
• Ability and willingness to provide informed consent.

You may not qualify if…

• Left main coronary stenosis of 50% or greater.
• CCTA lesions demonstrating stenosis >90% ("subtotal"), or complex, high-risk plaque characteristics resulting in an a priori recommendation for triage to CATH by the CCTA interpreting physician.
• Attending physician a priori decision for CATH.
• Previous coronary stent, coronary bypass or prior known myocardial infarction.
• Clinical instability, such as hypotension, signs of shock, and/or accelerating chest pain requiring admission.
• Pregnancy

Where it is running

• Beaumont Health System - Royal Oak — Royal Oak, Michigan, United States

Full record on ClinicalTrials.gov

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