Modeling the Neurological Basis and Characterizing the Neurological Phenotype of Obesity Using Human Neural Stem Cells

Stopped early

Conditions studied: Obesity, Morbid

In brief

This study aims to characterize the neurological basis of obesity and response to surgical and medical treatment by inducing adult pluripotent stem cells into neuronal cells from subjects that have demonstrated extreme response to bariatric surgery or pharmacological treatment for obesity.

Key facts

Study ID

NCT03263390

Run by

University of California, San Diego

People needed

6

Starts

2017-10-05

Expected to finish

2020-08-10

Last updated by the study team

2020-12-16

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• History of obesity
• Treatment with bariatric surgery
• Treatment with anti obesity medications
• Greater than 70% excess weight loss at least 6 months after surgery
• Greater than 15% weight loss on anti obesity medications

You may not qualify if…

• Active cancer, not including non-melanoma skin cancer
• Active eating disorder
• Use of anti obesity medications in subjects with a history of bariatric surgery
• Active complication of the upper GI tract in patients with a history of bariatric surgery

Where it is running

• University of California San Diego — La Jolla, California, United States

Full record on ClinicalTrials.gov

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