Use of IV Acetaminophen in the Treatment of Post Operative Pain in Patients Undergoing Craniotomy and Spine Surgery

Status unconfirmed · Not applicable · Has a placebo group

Conditions studied: Postoperative Pain

In brief

The purpose of this study is to investigate the effectiveness of intravenous acetaminophen (Tylenol) for post operative pain control in patients undergoing craniotomies (brain surgery) and spine surgery. Studies have shown that intravenous acetaminophen is useful for post operative pain control in some operations but there have not been studies to evaluate the use of acetaminophen in craniotomies or spine surgery.

Key facts

Study ID

NCT03261310

Run by

Brooke Army Medical Center

People needed

55

Starts

2013-05-01

Expected to finish

2018-07-01

Last updated by the study team

2017-08-25

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18-90 years old
• undergoing non-emergent craniotomy or single level lumbar laminectomy
• must be able to rate pain on a 0-10 scale post-operatively

You may not qualify if…

• history of liver disease
• allergy to acetaminophen
• age less than 18 years
• renal failure with creatinine clearance less than 30
• pregnancy
• altered mentation with inability to report pain score
• patients who have received acetaminophen within 6 hours of surgery
• patients in which a neuraxial technique has been performed for surgery
• prisoners

Where it is running

• Brooke Army Medical Center — San Antonio, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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