Telephone-Delivered Exercise for Multiple Sclerosis Fatigue

Completed · Not applicable

Conditions studied: Multiple Sclerosis, Fatigue, Physical Activity

In brief

Multiple sclerosis (MS) is a progressive demyelinating disorder that damages white matter in the central nervous system. Although individuals experience mobility (e.g., walking, balance) impairments that lower quality of life and limit participation in daily activities, one of the most prominent symptoms is fatigue. Up to 92% of individuals report fatigue that manifests as lack of energy, exhaustion or worsening of MS symptoms and ultimately contributes to increasing disability. The currently available pharmaceutical treatments fail to fully control fatigue in the majority of individuals with MS; non-pharmacologic therapies such as exercise and behavioral therapies offer the best hope for combating MS fatigue in the majority of individuals. Exercise therapy is effective in reducing MS fatigue. However, access to exercise therapy is seriously limited for many individuals with MS due to geographical location, limited resources (e.g., financial, transportation), and/or disability. Thus, the development and evaluation of an alternative delivery method for exercise therapy to target MS-related fatigue that increases participation and reduces barriers is critical. In this study, the investigators will compare traditional in-person delivered exercise therapy to telephone-delivered exercise therapy to target fatigue in persons with MS.

Key facts

Study ID

NCT03256851

Run by

Wayne State University

People needed

20

Starts

2017-06-01

Expected to finish

2018-07-31

Last updated by the study team

2019-10-30

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of RRMS, SPMS, or PPMS
• Ambulatory for at least 5 minutes at a time
• Self-reported fatigue on Fatigue Severity Scale
• Able to follow study-related commands
• Able to attend study appointments

You may not qualify if…

• MS exacerbation within the past 30 days
• Evidence of another neurological disorder or orthopedic disorder that would interfere with exercise participation
• Acute illness or injury that prevents participation in the intervention
• Pregnancy

Where it is running

• Wayne State University — Detroit, Michigan, United States

Full record on ClinicalTrials.gov

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