Adverse Airway Effects From Tobacco and E-Cigarettes

Status unconfirmed · Not applicable

Conditions studied: Airway Morbidity, Smoking Cessation, Nicotine Adverse Reaction, Smoking, Tobacco, Smoking, Cigarette

In brief

The purpose of the study conducted at VA Medical Center in Miami is to determine if smoking electronic cigarettes (known as e-cigarettes) that contain nicotine have less negative effects than regular cigarettes on the person's respiratory health. We will assess this by measuring pulmonary function tests, several body molecules and functionality of the airway cells. We will also evaluate how smokers can maintain exclusive electronic cigarettes use. In this study, some people will continue to smoke regular tobacco cigarettes while others will switch to a nicotine-containing electronic cigarette.

Key facts

Study ID

NCT03251053

Run by

Miami VA Healthcare System

People needed

200

Starts

2016-03-28

Expected to finish

2021-03-28

Last updated by the study team

2017-08-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects that actively smoke and have a history of at least 5 pack-years

You may not qualify if…

• HIV,marijuana use, asthma and other concomitant inflammatory pulmonary disorders, subjects with known pulmonary diseases including malignancies, subjects with prior thoracic surgery and subjects that used oral corticosteroids or antibiotics within the prior 3 months, subjects with allergies to study medications and subjects incapable of providing informed consent.

Where it is running

• Miami VA Healthcare System — Miami, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

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