Optimal Timing of Percutaneous Intervention in Non-maturing Dialysis Fistulas

Completed · Not applicable

Conditions studied: Immature Arteriovenous Fistula

In brief

Arteriovenous fistulas (AVFs) are the preferred type of vascular access for dialysis, but many of them fail to mature. The optimal timing of intervention to salvage immature AVFs is unknown.The study proposes a randomized clinical trial comparing the clinical and economic impact of early vs late angioplasty in non-maturing AVFs. The study proposes a RCT to test the hypothesis that, as compared to early angioplasty of non-maturing AVFs, late angioplasty results in a lower proportion of AVFs being used at 6 months, but a greater long-term AVF patency , lower requirement of subsequent interventions to maintain AVF patency for dialysis, and lower overall cost of access maintenance.

Key facts

Study ID

NCT03245944

Run by

University of Alabama at Birmingham

People needed

8

Starts

2018-03-01

Expected to finish

2020-03-01

Last updated by the study team

2020-04-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with End stage renal disease (ESRD).
• Patients on hemodialysis.
• Patients using central venous catheter (CVC).
• Patients who had a new AVF created after commencing dialysis.
• Patients who had immature fistula ( 6-week postoperative ultrasound that revealed an immature AVF (diameter < 4 mm diameter or blood flow < 500 ml/min).

You may not qualify if…

• Children with Age below 18

Where it is running

• UAB — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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