Predictors of AAA Expansion and/or Rupture

Stopped early · Phase 4

Conditions studied: Abdominal Aortic Aneurysm (AAA)

In brief

Eligible subjects in this study will have either a known abdominal aortic aneurysm (AAA) or because they do not have an AAA (control group). The purpose of this research study is to further study, through FEA, changes that occur in the mechanical properties of the aortic wall. The investigator will compare two radiotracers, 18F-FDG and 11C-PBR28 to determine if one provides more useful and reliable information about inflammation. 18F-FDG and 11C-PBR28 are radioactive drugs that will be used for imaging during the PET-CT scan. The investigator will also compare the results describing the mechanical properties of the AAA wall to the degree of inflammation in that wall as determined by PET-CT imaging to define new and better predictors of AAA growth and/or rupture.

Key facts

Study ID
NCT03231397
Run by
Washington University School of Medicine
People needed
2
Starts
2017-08-01
Expected to finish
2020-04-30
Last updated by the study team
2021-07-09

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.