The Effect of Yoga on Cardiac Sympathetic Innervation Evaluated by I-123 mIBG

Withdrawn before enrolling · Not applicable

Conditions studied: Heart Failure, Systolic

In brief

The purpose of this study is to evaluate if yoga practice will reduce cardiac sympathetic activity and subsequently cardiac arrhythmias.

Key facts

Study ID

NCT03227393

Run by

University of Cincinnati

People needed

0

Starts

2017-09-30

Expected to finish

2017-10-27

Last updated by the study team

2018-03-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Negative pregnancy test in females
• Ejection Fraction </= 40% assessed by echocardiogram within the last 12 months
• Stable dose of heart failure medications including afterload reducing medication such as ACE-I, ARB and hydralazine; beta blockers; digoxin and aldosterone antagonist for at least 4 months and no anticipated changes for 8 weeks. (i.e. no greater than a 50% dose change within the past month)
• Has an implantable pacemaker or ICD
• NYHA II-IV

You may not qualify if…

• pregnant or lactating female
• females without a pregnancy test
• co-administration of a positive inotrope (i.e. milrinone or dobutamine)
• history of significant medical non-compliance
• unwilling to adhere to the protocol
• Orthopedic limitation making yoga participation difficult
• Underlying cardiac rhythm other than sinus rhythm
• Recent history within 6 months prior to enrollment of unstable coronary artery disease (unstable angina, recent heart attack, recent revascularization, or decompensated heart failure)
• implantation of a cardiac resynchronization therapy device in the past 3 months.
• TIA, CVA, or major surgery in the past 3 months
• iodine or adreview (123-MIBG) allergy

Where it is running

• University of Cincinnati Medical Center — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.