Sleep Apnea, Cardiovascular and Exercise Study

Completed · Not applicable

Conditions studied: Obstructive Sleep Apnea, Vascular Diseases, Obesity

In brief

Obstructive sleep apnea (OSA) results in vascular dysfunction, which increases the risk of cardiovascular disease. In contrast, exercise confers cardioprotection through improvements in vascular health. This proposal evaluates whether the beneficial effects of exercise on vascular function are attenuated in obese individuals suffering from untreated OSA.

Key facts

Study ID

NCT03219749

Run by

Towson University

People needed

60

Starts

2017-01-15

Expected to finish

2019-06-30

Last updated by the study team

2019-09-10

Who can join

Age: 30 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• BMI between 30 and 42

You may not qualify if…

• Apnea-hypopnea index > 60 events (confirmed with overnight sleep study)
• Currently participating in an exercise program as defined as a minimum of moderate exercise > 30 minute/day, > 3 times or 90 minutes per week
• Participating in a weight loss program and NOT weight stable for 3 months
• History of heart disease
• Uncontrolled hypertension
• Cigarette smoking in the last 6 months
• Type 1 diabetes
• Women who are pregnant
• Currently using hormonal replacement therapy
• Comorbid conditions including concern, peripheral arterial disease, renal disease, lung disease, thyroid diseases, osteoporosis and arthritis with chronic joint pain

Where it is running

• Towson University Wellness Center — Towson, Maryland, United States

Full record on ClinicalTrials.gov

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