Microbiome Involvement With Barrett's Esophagus and Progression to Esophageal Adenocarcinoma

Status unconfirmed

Conditions studied: Barrett Esophagus, Esophageal Cancer

In brief

This study will examine the hypothesis that altered esophageal microbiome leads to the development of esophageal adenocarcinoma (EAC). The aims of the project are, firstly the confirmation of relational data on the study cohort, using the methods developed and applied at the laboratory at University of Queensland Diamantina Institute (UQDI). Second, to generate a tissue microarray resource future tissue in-situ validation of microbes. And finally, to develop a biobank of clinical isolates of relevant esophageal microbes for future functional studies.

Key facts

Study ID

NCT03216135

Run by

Ochsner Health System

People needed

50

Starts

2017-07-20

Expected to finish

2017-12-01

Last updated by the study team

2017-07-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or females >18 years of age with known or suspected GERD, Barrett's Esophagus and or esophageal adenocarcinoma or from patients who have a history of either condition.

You may not qualify if…

• None

Where it is running

• Ochsner Health System — Kenner, Louisiana, United States (enrolling)

Full record on ClinicalTrials.gov

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