Transcranial Infrared Laser Stimulation (TILS) of Prefrontal Cognition in Post-traumatic Stress Disorder (PTSD)
Stopped early · Not applicable · Has a placebo group
Conditions studied: Post-traumatic Stress Disorder (PTSD)
In brief
This study evaluates the effects of transcranial infrared laser stimulation (TILS) on prefrontal metabolism and hemodynamics in veterans with post-traumatic stress disorder (PTSD). The subjects will receive six TILS interventions and one sham intervention in a course of seven weeks.
Key facts
- Study ID
- NCT03209882
- Run by
- The University of Texas at Arlington
- People needed
- 10
- Starts
- 2017-10-01
- Expected to finish
- 2019-10-08
- Last updated by the study team
- 2021-07-23
Who can join
Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- War-zone and non-war-zone veterans
- Ages 18-60 years old
- Males and females
- Able to read, speak, and understand English
- Medical records showing prior diagnosis of PTSD (here it refers to the records prior to TILS, which will be assessed and obtained in Visit 1)
- Medical records showing diagnosis of PTSD (here it refers to the CAPS-5 record prior to TILS, which will be assessed and obtained in Visit 1)
- On stable doses of any psychotropic medications for at least 4 weeks
You may not qualify if…
- Significant physical disability to perform a computerized memory task
- Past/current significant medical/neurological/mental health disorders known to affect cognitive functioning (e.g., stroke, dementia, schizophrenia, AIDS)
- Presence of moderate/severe TBI, defined as having: alteration of consciousness/mental state >24 hours; posttraumatic amnesia >1 day; loss of consciousness >30 minutes; and/or abnormal structural neuroimaging. We will not exclude veterans with mild TBI, which is found in nearly 50% of veterans with PTSD
- Alcohol abuse/dependence for the past 12- months, as determined by the Rapid Alcohol Problems Screen score >0
- Drug abuse/dependence for the past 12- months, as determined by the Drug Abuse Screening Test-10 score >2
- Severe depression (PHQ-9 total score >19), significant risk of suicide (SBQ-R >6), severe headache (PHQ-15, Item e =2), and/or severe dizziness (PHQ-15, Item g =2)
- Opiate use in the month prior to study entry
Where it is running
- Engineering Research Building (ERB), University of Texas Arlington — Arlington, Texas, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.