Investigation of Cecal Intubation Rates and Pain Levels Between Water Exchange and Air Insufflation Flexible Sigmoidoscopy
Completed · Not applicable
Conditions studied: Colorectal Cancer
In brief
This study evaluates how often patients without sedation that receive screening sigmoidoscopy are able to have their full colon examined without significant discomfort by comparing a new colonoscopy technique known as the water exchange technique to the traditional air insufflation technique. It compares the differences between complete colon exam rates for water exchange when compared to the traditional air technique. Patients will be randomised and blinded to the procedure type. Previous studies have shown that the water exchange method is associated with a significant reduction in discomfort and often allows patients to receive colonoscopy without sedation or with only minimal sedation. However, the potential for water exchange to be used in the screening setting has yet to be evaluated. As per standard practices in sigmoidoscopy screening, patients will not be sedated. However, unlike standard practices in sigmoidoscopy screening, while maintaining minimal levels of discomfort, the investigators will attempt to scope beyond the distal colon.
Key facts
- Study ID
- NCT03209349
- Run by
- Kelowna Gastroenterology Associates
- People needed
- 90
- Starts
- 2017-06-14
- Expected to finish
- 2022-11-03
- Last updated by the study team
- 2022-11-07
Who can join
Age: 50 and older, up to 74. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Asymptomatic average risk (as per BC colon screening guidelines) individuals
- Ages 50-74 years of age
You may not qualify if…
- A sigmoidoscopy or colonoscopy within 10 years,
- A FIT within 2 years,
- Individuals classified with any high-risk screening criteria in accordance to the
- BC colon screening guidelines including:
- a personal history of adenoma,
- a first degree relative that was diagnosed with colorectal cancer or multiple adenomas under the age of 60,
- two or more first degree relatives with colorectal cancer at any age, longstanding inflammatory bowel diseases,
- a family history of familial adenomatous polyposis or hereditary nonpolyposis colorectal cancer, - Individuals presenting with rectal pain, rectal bleeding, abdominal pain, or unintentional weight loss at the time of the examination.
Where it is running
- Sepulveda Ambulatory Care Center — North Hills, California, United States
- Brent Parker — Kelowna, British Columbia, Canada
Full record on ClinicalTrials.gov
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