Effects of Carbohydrate in Diet and Supplements on the Gastrointestinal Tolerability of LIK066

Completed · Phase 2

Conditions studied: Obesity

In brief

The purpose of this study was to determine if LIK066 taken with a meal containing low carbohydrate is associated with less diarrhea compared to a high carbohydrate meal and to assess the potential effects of supplements such as psyllium or calcium carbonate on alleviating diarrhea associated with LIK066.

Key facts

Study ID

NCT03198767

Run by

Novartis Pharmaceuticals

People needed

54

Starts

2017-06-21

Expected to finish

2017-09-04

Last updated by the study team

2021-01-05

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• obese and overweight, BMI 25-50, HbA1C <10%

You may not qualify if…

• Preexisting, clinically significant cardiovascular, liver, renal, or GI disease that is considered unstable; pregnancy, Type 1 diabetes; Other protocol-defined inclusion/exclusion criteria may apply

Where it is running

• Novartis Investigative Site — Lincoln, Nebraska, United States

Full record on ClinicalTrials.gov

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