Linking Epidermal Barrier Function With Anti-Oxidant Defense Mechanisms in Skin Conditions

Stopped early

Conditions studied: Atopic Dermatitis, Hidradenitis Suppurativa, Contact Dermatitis, Psoriasis

In brief

Investigators will sample the skin and blood of patients with chronic skin conditions (including but not limited to atopic dermatitis (AD), contact dermatitis, hidradenitis suppurativa (HS), and psoriasis) to study the expression of anti-oxidative enzymes, skin barrier proteins and inflammatory molecules. In patients with atopic dermatitis, investigators will also measure skin barrier function using noninvasive devices. These results will be correlated with the disease severity in atopic dermatitis patients.

Key facts

Study ID

NCT03198390

Run by

University of Arizona

People needed

100

Starts

2017-08-04

Expected to finish

2020-05-31

Last updated by the study team

2021-06-04

Who can join

Age: 18 and older, up to 99. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male and female 18 to 99 years of age. Chronic skin conditions (including but not limited to atopic dermatitis, contact dermatitis, hidradenitis suppurativa, and psoriasis) with at least one active skin lesion Healthy skin (defined no clinical evidence or diagnosis of inflammatory skin conditions)

You may not qualify if…

• Subjects who are unable to comply with study procedures.

Where it is running

• University of Arizona - Banner University Medicine Dermatology — Tucson, Arizona, United States

Full record on ClinicalTrials.gov

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