Feasibility of an 8-week Tai Chi Chuan Intervention for Breast Cancer Survivors

Completed · Not applicable

Conditions studied: Cancer, Breast, Cognitive Impairment

In brief

Purpose:To gather preliminary data and to determine the feasibility and acceptability of an 8-week Tai Chi intervention for adults cancer survivors (survivors) who report experiencing cognitive impairment, and to perform exploratory analyses to assess improvements in cognitive performance, health-related quality of life, brain activity, and blood-based biomarkers. Participants: Adult survivors (\> 18 years old) who report experiencing cognitive impairment and are within 60 months of completion of chemotherapy for treatment of a breast cancer diagnosis. Procedures (methods): A single arm pre-/post-test non-randomized study design in adult cancer survivors (Enrollment goal N=15; current age ≥ 18 years, treatment completed within 60 months). Outcomes will be assessed at baseline and after the 8-week Tai Chi intervention, and consist of feasibility, acceptability, expectancy/credibility, health-related quality of life, cognitive performance, serum biomarkers, and brain activity.

Key facts

Study ID

NCT03196037

Run by

UNC Lineberger Comprehensive Cancer Center

People needed

4

Starts

2017-12-05

Expected to finish

2018-12-07

Last updated by the study team

2019-03-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Was diagnosed with breast cancer (all stages accepted).
• Currently > 18 years of age
• Age at cancer diagnosis > 18 years.
• Able to engage in moderate intensity exercise as determined by their treating physician. If participant no longer has a treating physician, safety will be determined by following the American College of Sports Medicine (PAR-Q \& YOU) physical activity questionnaire. An answer of "yes" to > one of the seven questions will require the participant to receive written permission from their physician prior to beginning the Tai Chi intervention.
• Not previously engaged in regular exercise training (>1-2d/wk for >30 min/d) in past 6 months.
• Completed chemotherapy treatment for a breast cancer diagnosis.
• Cancer chemotherapy treatment completed within last 60 months. Defined as not currently scheduled for or undergoing active treatment (chemotherapy, radiation, surgery). Treatments to prevent or delay recurrence (e.g., breast cancer hormonal therapies) or for maintenance of remission are allowed.
• Report experiencing cognitive impairment following treatment for cancer.
• No psychiatric disorder with psychotic features.
• Able to receive emails from study staff (i.e. for receiving study reminders).
• Able to speak and read English.
• Able to provide informed consent.

You may not qualify if…

• Unwilling or unable to complete study procedures.
• Currently participating in another study which would preclude participation in this study.
• Has a known additional malignancy that is metastatic, progressing, or requires active treatment.
• Has a neurocognitive disorder of other etiologies, such as Alzheimer's Parkinson's, etc., that might confound the analysis

Where it is running

• UNC Chapel Hill Program on Integrative Medicine — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

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