Development of a Rehabilitation Strengthening and Mobility Program for Ventilator Dependent Older Patients
Completed · Not applicable
Conditions studied: Respiration, Artificial, Critical Illness, Chronic Disease, Exercise Therapy, Rehabilitation, Physical Therapy Modalities
In brief
As the general population ages and technology advances, many who suffer from catastrophic critical illness (i.e. septic shock, respiratory failure, Acute Respiratory Disease Syndrome) survive only to find themselves severely physically debilitated and compromised from a pulmonary standpoint, requiring assistance from a mechanical ventilator in order to breath. Oftentimes, these patients require a long course of physical rehabilitation and ventilator support. These patients frequently remain ventilator dependent for greater than 3 weeks, and are thus referred to as requiring prolonged mechanical ventilation (PMV). Older patients are at significantly higher risk for requiring PMV for reasons that are not entirely clear, but which may include physical deconditioning, impaired cardiopulmonary physiology, and cognitive or behavioral disturbances. The purpose of this study is two fold: 1. to characterize the functional phenotype of ventilator dependent, and recently ventilated patients with respect to general strength, endurance, balance, and pulmonary functioning and body composition. 2. To pilot test a rehabilitation protocol that targets improving this populations disabilities through exercises focused on improving strength, endurance, balance, and pulmonary functioning.
Key facts
- Study ID
- NCT03195127
- Run by
- University of Maryland, Baltimore
- People needed
- 33
- Starts
- 2011-06-28
- Expected to finish
- 2017-02-01
- Last updated by the study team
- 2026-07-16
Who can join
Age: 20 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 20 or greater
- Received prolonged mechanical ventilation for >= 14 days during their last acute hospitalization
- Has received mechanical ventilation within the past 14 days for at least 6 hours in a 24 hour period
- Tracheostomy in place
- Subject is able to follow commands, and can give written or witnessed verbal consent in English
- Subject is eligible for physical rehabilitation
- All four limbs intact and mobile
You may not qualify if…
- Acute superimposed cardiopulmonary disease (ie.pulmonary edema, Stage IV congestive heart failure, COPD exacerbation, asthma attack, untreated infections, other)
- Severe functional impairment or physical impairment to rehabilitation
- Dementia, cognitive impairment (see attached description outlining cognitive impairment under additional documents)
Where it is running
- U of Maryland, Baltimore, Professional Schools IRB — Baltimore, Maryland, United States
Full record on ClinicalTrials.gov
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