Alkaline Phosphatase Level in Pregnancy and Its Association With Birth Weight

Completed

Conditions studied: Low Birth Weight Infants

In brief

Alkaline phosphatase is known to be produced by syncytiotrophoblasts in the placenta and its levels are normally increased in pregnancy. Therefore, it would be reasonable to hypothesize that alkaline phosphatase would be low to low normal in cases of low birth weight / intrauterine growth restriction (IUGR)/ placental insufficiency.

Key facts

Study ID

NCT03187938

Run by

TriHealth Inc.

People needed

292

Starts

2017-06-14

Expected to finish

2019-08-05

Last updated by the study team

2019-08-28

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Patients enrolled between 24w0d and 28w6d weeks gestational age will be included. The blood specimen of the patients enrolled will be held until delivery.

You may not qualify if…

• Multiple gestations
• Known congenital malformations (any, except Pyelectasis)
• Chronic hypertension
• Inflammatory bowel disease (IBD)
• Gall bladder disease
• Active bone disease (ie, skeletal dysplasia, healing fracture)
• Active liver disease (ie, hepatitis, cholestasis, cholelithiasis (gallstones))
• Pre-existing type 1 and 2 Diabetes
• Early-onset IUGR

Where it is running

• Good Samaritan TriHealth Hospital — Cincinnati, Ohio, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.