Antibiotic Resistance and Microbiome in Children Aged 6-59 Months in Nouna, Burkina Faso
Completed · Phase 4 · Has a placebo group
Conditions studied: Child Development
In brief
The use of antibiotics has saved millions of human lives, however consumption of antibiotics can select for antibiotic resistant organisms and may lead to changes in commensal microbiome. This study is designed to estimate the effect of antibiotic consumption on microbiome in a rural region of rural Burkina Faso. Changes in the intestinal and nasopharyngeal microbiome and resistome following a short course of antibiotics will be measured.
Key facts
- Study ID
- NCT03187834
- Run by
- University of California, San Francisco
- People needed
- 252
- Starts
- 2017-07-04
- Expected to finish
- 2019-09-01
- Last updated by the study team
- 2023-03-02
Who can join
Age: 1 and older, up to 5. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Households will be eligible for inclusion in the study if they have 2 or more children aged 6 months to 59 months currently residing in the household. Children from the household will be eligible if they are 6-59 months of age and are not currently receiving antibiotic treatment
You may not qualify if…
- Children who are allergic to any of the study antibiotics will be excluded. Individuals aged under 6 months and 5 years or older will be excluded. Children already receiving antibiotics for an ongoing disease will be excluded.
Where it is running
- UCSF Proctor Foundation — San Francisco, California, United States
- Centre de Recherche en Santé de Nouna — Nouna, Burkina Faso
Full record on ClinicalTrials.gov
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