Implementing Preemptive Pharmacogenomic Testing for Colorectal Cancer Patients in a Community Oncology Clinic
Completed · Not applicable
Conditions studied: Colorectal Cancer
In brief
Pharmacogenomics (PGx) studies the interactions between an individuals genes and medications. PGx testing identifies genes within an individual that may affect treatment, efficacy, and toxicity of drugs. With improvements in testing speed, accuracy and cost, it is now possible to perform PGx testing in cancer patients prior to starting chemotherapy. The test results may help a physician personalize chemotherapy dosing. The goal of this study is to determine if PGx testing using the OneOme® Rightmed test is feasible in a community oncology clinic to guide treatment prior to starting chemotherapy. The study will also gather data regarding the frequency of genes within the local population as well as the impact of testing on chemotherapy doses.
Key facts
- Study ID
- NCT03187184
- Run by
- Essentia Health
- People needed
- 40
- Starts
- 2017-05-20
- Expected to finish
- 2019-06-30
- Last updated by the study team
- 2019-10-22
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Histologically proven Stage 2-4 colon or rectal adenocarcinoma with an anticipated need for chemotherapy, which may include neoadjuvant, adjuvant or palliative treatment, and may include oral or intravenous chemotherapy.
- Adequate organ function and performance status to receive chemotherapy as determined by the treating physician.
- Age ≥ 18 years.
- Ability to understand and the willingness to sign a written informed consent documented.
- Patients must sign consent within 7 days of the physician visit for newly diagnosed or recurrent colorectal cancer when a patient is initially felt to be a candidate for chemotherapy.
You may not qualify if…
- Patients received prior chemotherapy for colorectal cancer in the last 12 months.
- Patients received prior OneOme RightMed® pharmacogenomic testing.
Where it is running
- Essentia Health — Duluth, Minnesota, United States
Full record on ClinicalTrials.gov
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