ECOSPOR IV: An Open-Label Study Evaluating SER-109 in Recurrent Clostridioides Difficile Infection
Completed · Phase 3
Conditions studied: Clostridioides Difficile Infection
In brief
Cohort 1: Subjects who had a Clostridioides difficile infection (CDI) recurrence in study SERES-012 within 8 weeks of receipt of study drug will be eligible. The purpose of this cohort is to assess safety and efficacy of SER-109 in reducing recurrence of CDI in adults who had a CDI recurrence within 8 weeks after receipt of SER-109 or Placebo in study SERES-012. Cohort 2: Cohort 2 is an open-label program for subjects who were not part of SERES-012. The purpose of this cohort is to describe safety and tolerability of SER-109 in subjects 18 years of age or older with at least a first recurrence of CDI.
Key facts
- Study ID
- NCT03183141
- Run by
- Seres Therapeutics, Inc.
- People needed
- 263
- Starts
- 2017-10-23
- Expected to finish
- 2022-04-29
- Last updated by the study team
- 2023-04-10
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- (Investigator site) — Sun City West, Arizona, United States
- (Investigator site) — Mather, California, United States
- (Investigator site) — Mountain View, California, United States
- (Investigator site) — Murrieta, California, United States
- (Investigator site) — Northridge, California, United States
- (Investigator site) — Sacramento, California, United States
- (Investigator site) — San Bernardino, California, United States
- (Investigator site) — San Diego, California, United States
- (Investigator site) — San Dimas, California, United States
- (Investigator site) — Simi Valley, California, United States
- (Investigator site) — Thousand Oaks, California, United States
- (Investigator site) — Clearwater, Florida, United States
- (Investigator site) — Clearwater, Florida, United States
- (Investigator site) — DeLand, Florida, United States
- (Investigator site) — Hialeah, Florida, United States
- (Investigator site) — Homestead, Florida, United States
- (Investigator site) — Jacksonville, Florida, United States
- (Investigator site) — Miami, Florida, United States
- (Investigator site) — Miami, Florida, United States
- (Investigator site) — Miami, Florida, United States
- (Investigator site) — Miami, Florida, United States
- (Investigator site) — Miami, Florida, United States
- (Investigator site) — Miami, Florida, United States
- (Investigator site) — Miami Lakes, Florida, United States
- (Investigator site) — Dothan, Alabama, United States
Full record on ClinicalTrials.gov
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