Effects and Mechanisms of Melatonin on Blood Pressure, Insulin Resistance, and Platelets

Completed · Not applicable

Conditions studied: Prehypertension, Healthy

In brief

The investigators will be studying the effect of melatonin on blood pressure, insulin resistance, and platelets, along with possible reasons for how melatonin cases these effects.

Key facts

Study ID

NCT03178396

Run by

Thomas Jefferson University

People needed

31

Starts

2015-12-07

Expected to finish

2016-08-09

Last updated by the study team

2017-06-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Normotensive (SBP <120) or prehypertensive (SBP = 120-139 mm Hg)
• Age: Young/middle-aged (ages 18-45) and (2) 10 elderly subjects ages 65 and older

You may not qualify if…

• Patients with a diagnosis of
• clinical hypertension and/or diabetes mellitus
• pregnancy
• coronary or cerebrovascular disease
• collagen vascular disease,
• organ failure (heart, kidney, liver).
• Patients taking anti-inflammatory medications: NSAIDs, corticosteroids, thiazolidinediones, and statins,
• Patients who have taken melatonin previously in the past year.

Where it is running

• Thomas Jefferson University — Philadelphia, Pennsylvania, United States

Full record on ClinicalTrials.gov

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