Genomic Profiling of Nodular Thyroid Disease and Thyroid Cancer

Status unconfirmed

Conditions studied: Thyroid Nodule, Thyroid Cancer, Thyroid Diseases, Thymic Carcinoma

In brief

The purpose of this registry is to collect uniform genomics-centered data on patients with nodular thyroid disease and cancer in a prospective fashion. After initial clinical evaluation patients with thyroid nodules will undergo standard ultrasonographic evaluation and a needle biopsy of the thyroid (fine needle aspiration (FNA) or core biopsy) as clinically indicated. Biopsy samples will be evaluated cyto-pathologically. A molecular/genomic profiling will be obtained using Thyroseq v2 test. Surgical treatment will be performed as per clinically determined indications. Standard surgical pathology will be processed and reported per the institutional policy and procedures. A molecular/genomic profiling will be obtained using Thyroseq v2 on the surgical specimen. All patients undergoing thyroid nodule work-up may be enrolled. The registry will collect patient demographic and clinical data, cytopathology reports, and surgical pathology reports and slides (if/when a review is required).

Key facts

Study ID

NCT03170804

Run by

Aventura Hospital and Medical Center

People needed

200

Starts

2017-01-01

Expected to finish

2020-01-01

Last updated by the study team

2017-05-31

Who can join

Age: 16 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients will be eligible for registry enrollment if they are undergoing thyroid nodule work-up.

You may not qualify if…

• Patients will not be eligible for registry enrollment if a work-up beyond clinical evaluation is not indicated.

Where it is running

• Aventura Hospital and Medical Center — Aventura, Florida, United States (enrolling)

Full record on ClinicalTrials.gov

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