Aerobic Treadmill Exercise And Metabolism

Completed · Not applicable

Conditions studied: Metabolism Disorder, Glucose, Physical Activity, Sedentary Lifestyle

In brief

Overview- In this study, overweight or obese, sedentary participants (age=35-55 years, n=20) will be randomized to a 12-week control period or an aerobic exercise intervention. Those randomized into the control group will then complete the exercise intervention subsequently. The planned energy expenditure per week of exercise will be 10-12 kilocalories per kilogram of body weight per week. Participants will complete three non-consecutive exercise sessions per week. Body weight, resting metabolic rate via indirect calorimetry, peak oxygen consumption (VO2peak) through graded exercise testing, fasting blood samples, CGM, sleep and dietary habits via self-report, and physical activity monitoring will be completed at prior to and following the aerobic exercise intervention.

Key facts

Study ID

NCT03162991

Run by

University of South Carolina

People needed

8

Starts

2017-11-13

Expected to finish

2019-04-15

Last updated by the study team

2019-04-18

Who can join

Age: 35 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• be age 35-55 years of age,
• have 25≤body mass index (BMI)≤40 kg/m2,
• be weight stable (±2%) during the previous 3 months,
• have ˂120 minutes of resistance or endurance exercise per week during the previous 3 months, and
• for females, be eumenorrheic, or post-menopausal for ≥1 year.

You may not qualify if…

• self-reported medical conditions (e.g. diabetes), cardiovascular diseases, chronic or recurrent respiratory conditions (e.g. uncontrolled asthma or chronic obstructive pulmonary disease), active cancer, and eating, or neurological disorders,
• medications that affect metabolism (e.g. thyroid medications, statins),
• psychological issues, including but not limited to untreated depression and attention deficit disorder,
• excessive caffeine use (>500 mg/day),
• smoking during the past year,
• pregnant or lactating females,
• unwillingness to provide informed consent.

Where it is running

• Public Health Research Center — Columbia, South Carolina, United States

Full record on ClinicalTrials.gov

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