The Influence of Atropine on Choroidal Thickness

Completed · Phase 4

Conditions studied: Myopia

In brief

Atropine eye drops are increasingly prescribed for the management of progressive myopia or short-sightedness. A previous study suggested that the back of the eye or choroid may be a part of the mechanism by which it induces its effects. The aim of this study is to characterize the effects of atropine on choroidal thickness and the influence of time of administration (am vs pm). It is hypothesized that the atropine's effect on choroidal thickness will vary with baseline thickness related to diurnal rhythm, where thicker baseline thickness will show a reduced choroidal response.

Key facts

Study ID

NCT03158142

Run by

State University of New York College of Optometry

People needed

32

Starts

2017-03-15

Expected to finish

2017-11-20

Last updated by the study team

2018-10-15

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Good general and ocular health
• Soft contact lens wearers to cease lens wear for at least 24 hours
• No previous rigid gas permeable lens wear

You may not qualify if…

• History of ocular surgery, including refractive surgery
• Amblyopia
• Use of ocular medications
• Known allergies or sensitivity to atropine
• Pregnant, plan to become pregnant, or are breastfeeding
• Taking monoamine oxidase inhibitors (MAOIs)

Where it is running

• State University of New York College of Optometry — New York, New York, United States

Full record on ClinicalTrials.gov

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