Pilot Data Collection for Activity, Adiposity, and Appetite in Adolescents

Completed

Conditions studied: Physical Activity, Sedentary Lifestyle, Metabolism, Energy Balance

In brief

The goal of this study is to quantify energy metabolism using indirect calorimetry at rest, in the presence of excess energy following a meal, and in response to the demand for energy during exercise. The investigators also will examine the individual and joint associations of activity and obesity status on neurocognitive domains of appetite control. Participants will include adolescent males and females (N=80) using a 2 x 2 cross-sectional study design, stratified by body weight (normal vs overweight/obese) and physical activity level (sedentary vs. active).

Key facts

Study ID

NCT03157063

Run by

Children's Mercy Hospital Kansas City

People needed

64

Starts

2017-01-01

Expected to finish

2018-11-19

Last updated by the study team

2021-04-26

Who can join

Age: 14 and older, up to 18. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Males (Tanner Stage III-IV), ages 14-18
• Weight stable (5% weight change) over the previous three months as assessed by self-report.
• BMI greater than 5th and less than 99th percentile
• Physically healthy for exercise as assessed by self report Physical Activity Readiness Questionnaire (PAR-Q) for children.
• For fMRI testing, all participants must be right handed and must have normal or corrected to normal vision (as they will be viewing pictures in the fMRI procedure).

You may not qualify if…

• History of restrained eating, eating disorders, bariatric surgery, or other significant medical diagnosis that could impact metabolism.
• Participants taking thyroid medications, beta blockers, or other stimulants (medications are known to affect physical activity level and metabolism).
• Due to fMRI procedure requirements, children with a history of Attention Deficit Hyperactivity Disorder (ADHD) or other diagnosed psychiatric issues will be excluded.

Where it is running

• Children's Mercy Kansas City — Kansas City, Missouri, United States

Full record on ClinicalTrials.gov

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